The circumstances surrounding the death of Alessandro 'Alex' Zanardi (1966-2026), the Italian motorsport legend and four-time Paralympic gold medalist, attributed to long-term complications from severe cranial and facial injuries sustained in a June 2020 handbike accident during the Obiettivo Tricolore relay race in Tuscany, Italy.

Reports indicate Zanardi, who had already lost both legs in a 2001 CART crash, endured multiple neurosurgeries and a medically induced coma post-2020 incident, with his passing at age 59 confirmed by family without specifying an exact medical cause, though linked to prior trauma.