Schedule 3 drugs, or Schedule III controlled substances under the U.S. Controlled Substances Act, are medications with moderate to low potential for physical and psychological dependence relative to higher schedules. They have accepted medical uses but may lead to abuse.

Examples include anabolic steroids, ketamine, certain codeine combinations (e.g., Tylenol with codeine), and testosterone. Possession typically requires a prescription, with penalties for misuse varying by jurisdiction.